Principal Biologist

Reports To: Chief Technology Officer

Main Roles & Responsibilities

Reporting to the Chief Technology Officer, and working closely with colleagues across the research team and the whole organisation, this role will require a PhD scientist with substantial experience including work at a strategic, operational and team leadership level. You will be a significant contributor to the development of scientific strategy and portfolio management, and you will be the contribute to decision making concerning new targets, biology assays to support our drug discovery programs, translational medicine research activities for each clinical programme, and in-licensing opportunities.

In particular, you will:


  • Design and lead the biology elements of research programmes in the Carrick portfolio
  • Advise and support data collection, sample collection, QC and regulatory processes
  • Interpret and report on outputs of screening and profiling activities
  • Liaise with medicinal chemists to devise strategy for optimisation and testing of compounds in development
  • Build up collaborations with external groups to further the biological understanding of the Carrick portfolio
  • Provide guidance on the strategy for patient stratification and identification of biomarkers to be used as part of a translational medicine strategy
  • Advise, and provide input on relevant aspects of clinical trial design

Team Leadership

  • Lead and supervise research at CROs and academic collaborations
  • Contribute to the selection of CRO organisations and academic collaborations

Strategy and Portfolio

  • Participate, in an expert role in the development of the research strategy.
  • Contribute to the assessment of in-licensing decisions and acquisitions into the Carrick Therapeutics portfolio, including due diligence reviews of the biology package for each potential new asset.

Position Requirements

The Principal Biologist should have a profile that is closely aligned to the following.

  • PhD with a relevant thesis, plus first degree in biology or closely related discipline
  • Demonstrable track record of achievements, enabling the progression and development of compounds in pharmaceutical/biotech organisations
  • Ten plus years’ experience in the pharmaceutical/biotechnology industry or post-doc, with significant organisations
  • A track record in identification of candidates for drug nomination and a comprehensive understanding and deep appreciation of the entire project cycle from discovery (target identification to candidate selection)
  • Experience of pre-clinical and clinical projects and influencing their translational medicine strategy
  • Proven ability to independently set up and manage external collaborations with leading academic and CRO’s
  • Ability to work effectively and achieve results in a multi-site organisation; co-operating with Carrick colleagues, external consultants and other stakeholders
  • A positive, constructive and team-oriented work style, able to operate through influence and effective communication, and able to engage others around common goals
  • Well organised, self-motivated and able to work with minimal supervision
  • High energy, commitment and willingness to align to the values of the business

To express interest in this position please send your current CV & Contact details here. Your application will be treated in strict confidence.

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At Carrick Therapeutics, we strive for the highest standards in handling applications and observance of equal opportunities. We do not accept unsolicited CVs sent by third parties and are under no obligation to either respond or react to them. If someone is interested in our company and what we have to offer, we advise them to contact us through the appropriate channels given above.