Cyclin Dependent Kinase 7 (CDK7) Inhibitor |
|
HR + Her2 - mBC
|
|
|
|
|
|
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+ fulvestrant (IM SERD)
|
FDA Fast Track Status
Discovery Phase complete
|
FDA Fast Track Status
Pre-Clinical Phase complete
|
FDA Fast Track Status
Phase 1 Phase complete
|
FDA Fast Track Status
Phase 2 Phase in progress
|
FDA Fast Track Status
Phase 3 Phase not started
|
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+ giredestrant (oral SERD)
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Discovery Phase complete
|
Pre-Clinical Phase complete
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Phase 1 Phase complete
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Phase 2 Phase in progress
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Phase 3 Phase not started
|
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+ elacestrant (oral SERD)
|
Discovery Phase complete
|
Pre-Clinical Phase complete
|
Phase 1 Phase complete
|
Phase 2 Phase in progress
|
Phase 3 Phase not started
|
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mCRPC anti-androgen combination
|
Discovery Phase complete
|
Pre-Clinical Phase complete
|
Phase 1 Phase in progress
|
Phase 2 Phase not started
|
Phase 3 Phase not started
|
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TNBC chemotherapy combination
|
FDA Fast Track Status
Discovery Phase complete
|
FDA Fast Track Status
Pre-Clinical Phase complete
|
FDA Fast Track Status
Phase 1 Phase in progress
|
FDA Fast Track Status
Phase 2 Phase not started
|
FDA Fast Track Status
Phase 3 Phase not started
|
|
Pancreatic cancer chemotherapy combination
|
Discovery Phase complete
|
Pre-Clinical Phase in progress
|
Phase 1 Phase not started
|
Phase 2 Phase not started
|
Phase 3 Phase not started
|
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SCLC chemotherapy combination
|
Discovery Phase complete
|
Pre-Clinical Phase in progress
|
Phase 1 Phase not started
|
Phase 2 Phase not started
|
Phase 3 Phase not started
|
|
Cyclin Dependent Kinase 12/13 (CDK12/13) Inhibitor / Cyclin K degrader |
|
Monotherapy: Fusion driven cancers (e.g. Ewing’s)
|
Discovery Phase complete
|
Pre-Clinical Phase in progress
|
Phase 1 Phase not started
|
Phase 2 Phase not started
|
Phase 3 Phase not started
|
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PARP inhibitor combination
|
Discovery Phase complete
|
Pre-Clinical Phase in progress
|
Phase 1 Phase not started
|
Phase 2 Phase not started
|
Phase 3 Phase not started
|
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Checkpoint inhibitor combination
|
Discovery Phase complete
|
Pre-Clinical Phase in progress
|
Phase 1 Phase not started
|
Phase 2 Phase not started
|
Phase 3 Phase not started
|
|